Orioles Opening Day 2025. The baltimore orioles have set the stage for their 2025 regular season, kicking things off on the road against the toronto blue jays on opening day, march 27, 2025. For the first time in a long time, the orioles' outfield could look quite different on opening day 2025.

Baltimore will open the 2025 season on thursday, march 27, in. Cincinnati), memorial day (may 26 vs.